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10% off your first order
Every lot ships with a public COA
Order by 2pm ET on weekdays, ships the same day
Save up to 20% with volume pricing
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Research peptide
Growth hormone-releasing hexapeptide · GHS-R1a agonist peptide
$34.99
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Earn 34 points with this purchase
SKU: GHRP6-5
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2–5 business days in transit after dispatch
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For research use only. Not for human consumption.
Copper tripeptide-1 (Gly-His-Lys·Cu2+) · copper-binding tripeptide
Technical specifications
Molecular profile
GHRP-6 (growth hormone-releasing hexapeptide; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) is a synthetic, C-terminally amidated hexapeptide containing two D-amino acids. It emerged from structure–activity work on met-enkephalin analogues and is one of the earliest characterised synthetic growth hormone secretagogues (GHS).
GHRP-6 is an agonist of the growth hormone secretagogue receptor type 1a (GHS-R1a), the G protein-coupled receptor later identified as the endogenous ghrelin receptor. Early studies described its specific GH-releasing activity in rat pituitary preparations in vitro and in vivo, and synthetic secretagogues of this class guided the subsequent cloning of GHS-R1a from pituitary and hypothalamus. It remains a widely used tool compound in studies of ghrelin-receptor signalling, somatotroph function and hypothalamic GHS binding sites in rodent and cell-based models.
Supplied as a lyophilized powder in a sealed vial.
For laboratory research use only. Not for human or veterinary use.
Storage requirements
Handling
Literature
2 publications for further reading. Cited for scientific context only.
Endocrinology · 1984
Bowers CY, Momany FA, Reynolds GA, et al.
Science · 1996
Howard AD, Feighner SD, Cully DF, et al.
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