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10% off your first order
Every lot ships with a public COA
Order by 2pm ET on weekdays, ships the same day
Save up to 20% with volume pricing
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Research peptide
TH9507 · trans-3-Hexenoyl-GHRH(1-44)-NH2, GHRH analogue peptide
$39.99
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SKU: TESA-5
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For research use only. Not for human consumption.
Technical specifications
Molecular profile
Tesamorelin (development code TH9507) is a synthetic 44-amino-acid analogue of growth hormone-releasing hormone (GHRH). It comprises the complete human GHRH(1-44) sequence with a C-terminal amide and an N-terminal trans-3-hexenoyl group. This N-terminal modification makes the peptide more resistant to cleavage by dipeptidyl aminopeptidase than native GHRH.
Tesamorelin acts as a GHRH receptor agonist on anterior pituitary somatotrophs, stimulating synthesis and release of endogenous growth hormone with downstream increases in insulin-like growth factor-1 (IGF-1). Its pharmacology and safety profile has been described in laboratory-animal studies, and it is used in research on GHRH receptor signalling, regulation of the somatotropic (GH/IGF-1) axis, and N-terminal modification strategies for stabilising peptide hormones against enzymatic degradation.
Supplied as a lyophilized powder in a sealed vial.
For laboratory research use only. Not for human or veterinary use.
Storage requirements
Handling
Literature
2 publications for further reading. Cited for scientific context only.
Basic & Clinical Pharmacology & Toxicology · 2007
Ferdinandi ES, Brazeau P, High K, et al.
Expert Opinion on Investigational Drugs · 2009
Tesamorelin, a human growth hormone releasing factor analogue (opens in a new tab)
Wang Y, Tomlinson B
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